Therapeuticindexdatabase

由 HS Blix 著作 · 2010 · 被引用 121 次 — Drugs with narrow therapeutic index (NTI-drugs) are drugs with small differences between therapeutic and toxic doses. The pattern of drug- ...

由 J Yin 著作 · 2021 · 被引用 7 次 — A narrow therapeutic index (NTI) of a drug implies that a tiny variation in the dosage of the drug might lead to treatment failure or severe adverse drug ...

2017年5月9日 — Narrow therapeutic index drugs are drugs where small differences in dose or blood concentration may lead to serious therapeutic failures and/or ...

Narrow therapeutic index (NTI) drugs are defined as those drugs where small differences in dose or blood concentration may lead to dose and blood concentration ...

由 J Tamargo 著作 · 2015 · 被引用 257 次 — The therapeutic index (TI) is the range of doses at which a medication is effective without unacceptable adverse events. Drugs with a narrow TI (NTIDs) have a ...

由 S Habet 著作 · 2021 · 被引用 25 次 — Historically, the identification of drugs with the Narrow Therapeutic Index (NTI) has been empirically based on the clinical practice.

由 RG Greenberg 著作 · 2016 · 被引用 61 次 — For some drugs, this approach offers a low-cost method of therapeutic index estimation. Our results can serve as preliminary data for future trials and as ...

2022年11月1日 — Narrow therapeutic index (NTI) drugs are drugs where small differences in dose or blood concentration may lead to serious therapeutic failures ...